Lynne Gershon Maxwell

Biographical Data

(CHOP) Lynne Maxwell, MD, FAAP is currently the deputy director of the Division of General Anesthesia in the Department of Anesthesiology and Critical Care at the Children’s Hospital of Philadelphia and Associate Professor of Anesthesiology and Critical Care at the University of Pennsylvania. Dr. Maxwell is a graduate of Harvard College and Johns Hopkins University School of Medicine. She is board certified in Pediatrics and Anesthesiology. Dr. Maxwell provides anesthesia for surgery and procedures in and out of the operating room, from fetal surgery to young adults. In addition, she serves as faculty on the pain service providing care for patients with both acute postoperative and chronic pain.

Dr. Maxwell served six years both as a member of the executive committee of the AAP Section on Anesthesiology and Pain Medicine and six years as an elected member of the AAP Committee on Drugs (COD). She is currently an elected member of the executive committee of the AAP Section on Clinical Pharmacology and Therapeutics. Dr. Maxwell participated in the FDA NICHD neonatal drug initiative, pain subgroup, which identified barriers to drug safety and efficacy studies in the neonatal population and drug categories with specific needs for study in newborns. Dr. Maxwell was a co-investigator in A Phase II Multicenter, Randomized, Double-blind, Parallel group, Dose-Ranging, Effect-Controlled Study to Determine the Pharmacokinetics and Pharmacodynamics of Sodium Nitroprusside (SNP) in Pediatric Subjects (NICHD 2003-09-DR), one of the studies to come out of the BPCA legislation to increase knowledge of drugs used in children. She has served on the advisory panel for pediatric drug list development under BPCA 2006 – 2009. Current clinical studies involve safety and efficacy of anesthetics and analgesics in neonates, infants and children.

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Lynne Gershon Maxwell's Publications:

  1. Emergent excision of a prenatally diagnosed sacrococcygeal teratoma.
  2. Pathophysiology and management of opioid-induced pruritus.
  3. Continuous peripheral nerve blockade for inpatient and outpatient postoperative analgesia in children.
  4. Protracted pain following partial splenic embolization in an adolescent female with hypersplenism.
  5. Anesthesia and analgesia during and after surgery in neonates.
  6. The effects of a small-dose naloxone infusion on opioid-induced side effects and analgesia in children and adolescents treated with intravenous patient-controlled analgesia: a double-blind, prospective, randomized, controlled study.
  7. Age-associated issues in preoperative evaluation, testing, and planning: pediatrics.
  8. Adverse effects of sedatives in children.
  9. Ensuring safety of patients receiving sedation for procedures: evaluation of clinical practice guidelines.
  10. Perioperative management issues in pediatric patients.
  11. The management of pain in sickle cell disease.
  12. Respiratory failure after laparoscopic cholecystectomy in a patient with chronic hemidiaphragm paralysis.
  13. Polysomnography after adenotonsillectomy in mild pediatric obstructive sleep apnea.
  14. Preanesthetic medication of children with midazolam using the Biojector jet injector.
  15. Bupivacaine-induced cardiac toxicity in neonates: successful treatment with intravenous phenytoin.
  16. Local anesthetics in the management of acute pain in children.
  17. Disposition and respiratory effects of intrathecal morphine in children.